Study of some hematological, and biochemical parameters in patients with sars-cov-2 in kirkuk city/iraq

Abstract

Background: Coronavirus disease 2019 (COVID-19) or so-called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has been implicated in cases of mild to severe diseases of the respiratory system. The World Health Organization (WHO) declared that SARS-CoV-2 infection is a pandemic infection. Objectives: Our study aimed at the detection of the relationship of some hematological and biochemical markers with SARS-CoV-2 infection in Kirkuk City/Iraq. Methods: A cross-sectional study performed at Kirkuk general hospital (May 15 to, August 25 /2020). It was done on a total of (84) patients (50 male and 34 female), who were aging between (16-70) years old. They already diagnosed with SARS-CoV-2 infection through having chest computerized tomography scan (CT-Scan) from (Simens Co.), and 60 non-infected with SARS-CoV-2, who used as a control group at similar age group. Blood samples taken from the patients and control group to test for; serum ferritin, D-dimer, blood urea, serum creatinine, lymphocytes and total white blood cells count. Results: The study revealed the highest rate (72%, and 42 %) of decreased white blood cells (WBCs) in male and female patients respectively; this was also true for the lymphocytes count where the patients showed the highest rate of decreased lymphocytes count. The majority of the patients showed increased levels of serum ferritin, D-dimer, blood urea, and serum creatinine. Most of the patients were from blood group A. Conclusions: Infection with SARS-CoV-2 may decrease the levels of WBCs and lymphocytes, while having reverse impact on the serum ferritin, D-dimer, blood urea and serum creatinine levels which increases them. Most of the patients from Kirkuk were from blood type A.