Abstract

Background: Breast lesions in females are heterogeneous diseases that consist of several distinct entities with remarkably different characteristic features. The present study was conducted to assess histopathological findings of excision biopsies of breast lesions.Subjects and Methods:The present study was conducted on 150 cases of lumpectomy breast specimens received in the department of histopathology. The histopathological diagnosis made after routine processing and hematoxlin and eosin staining.Results:The most common age group of presentation was 30 to 50 years having well defined breast mass lesion. The difference was significant (P< 0.05). Among 150 breast specimens, 145 found to be benign and 05 malignant. In benign, common lesions were fibroadenoma in 64, fibroadenosis in 30, Acute Suppurativeinflammatory lesion (Abscess) in 20, fibrocystic disease (FCD) in 22, duct papilloma in 05 and benign phyllodes in 04 cases. In malignant, 04 cases were infiltrative ductal cell carcinoma NOS (Not otherwise specified) and 01 carcinoma in situ. The difference was significant (P< 0.05).Conclusion: Authors found that most common benign breast lesions were fibroadenoma (44.1%) and fibroadenosis (20.6%) followed by acute suppurative inflammatory (Abscess) and FCD.

Highlights

  • The breast is a modified sweat gland composed of both epithelial and connective tissue elements

  • Majority of the breast lesions initially present with a lump in the breast which is very sensitive for female patients due to which they might not report timely to the doctor for an examination.[2]

  • Patients presented with palpable lump in the breast, mostly non tender and painless

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Summary

Introduction

The breast is a modified sweat gland composed of both epithelial and connective tissue elements. Majority of the breast lesions initially present with a lump in the breast which is very sensitive for female patients due to which they might not report timely to the doctor for an examination.[2] Benign or malignant lesions do not pose any problem in histopathological diagnosis. As the use of mammography becomes more widespread the number of benign biopsy specimens will increase and histopathologists should be aware of the spectrum of disorders responsible for non-palpable mammographic abnormalities.[4] The WHO statistics in 2008 states that malignant breast lesions comprise 1.38 million cases (10.9% of total cancer patients).

Results
Conclusion
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