Abstract

Objectives To detect the level of di-2 - ethylhexyl phthalate(DEHP) in serum and semen to evaluate effect of DEHP to idiopathic asthenaspermia. Methods 150 people were assigned into idiopathic asthenaspermia group( n = 50), no idiopathic asthenaspermia group ( n = 50 ) and nomal group ( n = 50 ). The concentrations of DEHP in the human biological samples were measured by using reversed-phase HPLC. Results The DEHP were detected in most of the idiopathic asthenaspermia group 0. 10 ～ 1. 5 mg / L in semen specimens, 15 of no idiopathic asthenaspermia group 0 ～0.96 mg/L in semen specimens, 13 of nomal group 0 ～0.95mg/L in semen specimens. There was difference between semen concentrations of DEHP and sperm molity ( p ＜ 0. 05 ). Conclusions These results suggest that DEHP affect semen quanlity,specialy DEHP in semen specimens. Key words: Oligospermia

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