Study of clinicohistopathological correlation of skin adnexal tumours

Abstract

Appendageal tumours (Appendageal tumours) are neoplasms which differentiate towards or arise from pilosebaceous apparatus, apocrine gland or eccrine sweat glands. Overall incidence of Appendageal tumours is low, yet they can be challenging to diagnose. The study aims at determining the frequency, profile, and distribution of skin adnexal tumours and association of their distribution with patient’s age and sex. Cross-sectional descriptive study, conducted over 1-year period. All clinically suspected cases of Appendageal tumours were evaluated and subjected to histopathological examination. Confirmed cases of Appendageal tumours were finally analyzed. : Out of 43586 new patients attending OPD, 64(0.14%) cases of Appendageal tumours were suspected. And 60 underwent histopathological examination. Histopathology was confirmatory in only 42 (70%) cases. Out of 42, the hair follicle tumors comprised of trichoepithelioma 18/42(42.85%), trichofolliculoma 1/42 (2.38%), pilomatricoma 4/42 (9.52%), and trichilemmal cyst 4/42 (9.52%). The sweat gland tumors are comprised of chondroid syringoma 12/42(28.57%), hidrocystoma 2/42(4.76%) and syringocystadenoma papilliferum 1/42(2.38%). Females (61.90%) outnumbered males (38.09%) in our study population. The incidence of benign skin Appendageal tumours is more as compared to the malignant ones as found in our study. Histopathology remains the gold standard for diagnosis of these tumours.