"Study Of Clinical Characteristics and Risk Determinants Of Patients With Prosthetic Valve Thrombosis: A Tertiary Care Hospital-Based Observational Study"

Sanjeev Asotra

doi:10.32474/acr.2021.03.000170

Abstract

Prosthetic valve replacement is the mainstay of treatment for patients with severe symptomatic valvular heart disease but in the process, the native valvular disease is exchanged with prosthesisrelated complications.

Highlights

Prosthetic valve thrombosis (PVT) is a rare but serious complication of valve replacement, most often encountered with mechanical prostheses
The most important risk factor attributed to the occurrence of prosthetic valve thrombosis was non-compliance to treatment leading to subtherapeutic INR
Mitral valve thrombosis was most commonly seen and Fibrinolysis can be considered as effective therapy even in patients presenting with NYHA Class III/IV especially in resource-stricken developing countries

Summary

Introduction

Prosthetic valve thrombosis (PVT) is a rare but serious complication of valve replacement, most often encountered with mechanical prostheses. The present study aims to evaluate patients with prosthetic valve thrombosis in terms of the clinical characteristics, risk determinants, treatment, and outcomes in the prospective observational study. Prosthetic valve replacement is the mainstay of treatment for patients with severe symptomatic valvular heart disease but in the process, the native valvular disease is exchanged with prosthesisrelated complications. The incidence of obstructive PVT for mechanical valves varies between 0.3-1.3-3% patient years[2,3]. The incidence ranges from 0.1% to almost 6% per patient-year for left-sided valves and up to 20% for tricuspid valves[4]

Methods

Results

Conclusion