Abstract
The present study analyzes the cannabinoids content in samples of Cannabis sativa L. cultivated illicitlyin Colombia. The physicochemical conditions are optimized for the extraction and quantification ofCannabidiol (CBD), 9-Tetrahidrocannabinol (THC) and Cannabinol (CBN) starting from a vegetablesample using gas chromatography with flame ionization detector (GC-FID), validating the respectiveanalytic method. Samples coming from four diferent Colombian regions are analyzed (Llanos Orientales,LL; Cauca, CA; Sierra Nevada de Santa Marta, SN; Eje Cafetero, EC). The study let determination ofCBD, THC and CBN samples quantitatively. The average content of THC in the samples of the regionLL is of 15.74% ± 2.92, in the region CA is of 10.98% ± 6.70, in the region SN is of 2.81% ± 1.72 andin the region EC of 1.87 % ± 1.25. The higher content of THC in vegetable samples of Cannabis from the Llanos Orientales (LL) and Cauca (CA) could be indicative of the employment of improved varieties. This fact generates a great concern about the potential effects produced by the drug in consumers.
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