Abstract
Polarographic measurements of endogenous Zn were made with soluble and insoluble fractions of several endocrine organs (pituitary gland, thyroid gland, parotid gland, submaxillary gland, thymus, pancreas, seminal vesicle and blood) of the male albino rats in normal and experimental conditions, in the latter of which animals were adrenalectomized and/or injected with DOCA or cortisone acetate.1. Injection of DOCA or cortisone into nomal rats did not change in the contents of Zn in the most of the organs, with two exceptions, one of which is significant decrease in Zn content in both of soluble and insoluble fractions obtained from the pancreas, and the other increase in Zn content in the testis.2. Zn contents in the most of the organs of the adrenalectomized rats showed a tendency to increase, which was recovered by injections with DOCA or cortisone. In pancreas, however, adrenalectomy together with the injections of the hormones showed significant decrease in the Zn contents.3. Increase of Zn contents in soluble and insoluble fractions induced by adrenalectomy was restored more efficiently by DOCA than by cortisone.
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