Abstract
Dimetacrine (1), 10-[3-(dimethylamino)propyl]-9,9-dimethyl-acridan, is a tricyclic compound with a central hexagonal ring instead of the heptagonal ring common to most antidepressants. Clinical properties and the value of this drug in the treatment of depressive states, and in a variety of psychic disorders have been well established (2,3). A previous paper (4) demonstrated the metabolic fate of dimetacrine by means of a radiometric assay.
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