Abstract
The case histories of three patients with unusual reactions to jellyfish envenomations or increased amounts of anti-jellyfish serum antibodies are presented. These cases demonstrated the following facts: (1) Allergic reactions may play a significant pathophysiologic role in jellyfish envenomation of humans. (2) Elevated specific anti-jellyfish immunoglobulins may persist for several years. (3) Recurrence of the clinical cutaneous reaction to jellyfish stings may occur within a few weeks without additional contact with the tentacles. (4) It is apparent that serologic cross-reactivity between the sea nettle and the man-of-war occur, as do false-positive enzyme-linked immunosorbent assay (ELISA) serologic tests to either jellyfish venom.
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