Abstract
The renin-angiotensin system in various forms of hypertension in younger adults, refractory edema and normal controls was studied by measurement of serum renin, of serum angiotensinase and angiotensin infusion test. The attitudes of the renin-angiotensin system in renovascular hypertension, malignant hypertension and primary aldosteronism were significantly different from that in normal controls. The renin-angiotensin system in refractory edema without hypertension was similar to that in renovascular hypertension. In hypertension with unknown cause, subjects with hypertensive disposition showed increased pressor response to angiotensin infusion in spite of normal levels of serum renin. The studies on the renin-angiotensin system by these examinations are useful for differentiation of various forms of hypertension.
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