Abstract
Emulsion is broken in two passages, by drainage and coalescence. In order to estimate the coalescence of emulsion, the constant amount of oil-in-water sample emulsion on a flat glass plate was dried by maintaining at relative humidity of 11%, and the coalescence of oil particles was accelerated. The increase in size of oil particles with time was measured by the turbidimetric method.As shown in Figs. 1, 2, and 3, where extinction was plotted in logarithmic scale against drying time, it was observed that the most plots were linear and consisted of two fairly well-defined regions, one in which the change of extinction was very little with time, and the other in which the decrease of extinction was much more rapid. There was a marked correspondence between the sustaining time to coalescence determined by this method and the shelf stability found at room temperature for long period, except for a viscous sample.
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Schedule a callMore From: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
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