Abstract

The susceptibility of Meriones unguiculatus to infection with several species of Leptospira was studied.It was found that L. icterohaemorrhagiae were virulent for Mer. unguiculatus and 4 to 10 week old gerbils challenged with more than 105 cells developed always lethal infections with hemorrhages in subcutaneous tissue and lungs and occasionally with jaundice. L. autumnalis proved also to be virulent, but both L. hebdomadis and L. australis A were avirulent in gerbils.The protective effect of homologous immune rabbit serum and the immunizing potency of vaccine in gerbils against infection with L. icterohaemorrhagiae were studied and the availability of gerbils in these experiments was demonstrated.

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