Abstract
Abstract: Proteins within cells vary widely in their rates of degradation. These rates appear to have evolved to regulate flow of substrates through metabolic pathways. Protein half-lives in vivo correlate with their sensitivity to various proteases in vitro . In mammalian tissues, proteins with acidic isoelectric points are degraded more rapidly than neutral or basic ones. Isoelectric point and subunit molecular weight are independent factors influencing protein degradative rates.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have