Abstract
SUMMARY The effects of intramuscular injection of atropine (0.6 mg), hyoscine (0.4 mg) and a placebo have been compared as premedication. Atropine did not differ from the placebo with regard to sedation and relief of apprehension but did produce a higher incidence of tachycardia. Hyoscine produced a high incidence of good or fair sedation and a very low incidence of tachycardia. The relative slowing of the heart compared with the placebo may be because of the good sedation or may be a specific: action of the drug. Anaesthesia with methohexitone and nitrous oxide showed a higher incidence of excitatory phenomena after hyoscine than after atropine. Respiratory upset (hiccough) was reduced by hyoscine, as was the incidence of emetic sequelae in the first hour after anaesthesia.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have