Abstract
Sodium dependent glucose transporters (SGLTs) are members of the large solute carrier (SLC) family of proteins that exploit the sodium ion concentration gradient to transport glucose across the plasma membrane. In humans, there are six subtypes (SGLT1-6) expressed widely in the small intestine, kidney, lung, muscle and brain. Due to their role in sugar reabsorption, SGLTs are currently exploited as a drug target for the treatment of type 2 diabetes, especially hSGLT2, which is responsible for 98% of glucose reabsorption in the kidneys.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
