Structure of Ribosomes and Their Components by Advanced Techniques of Electron Microscopy and Computer Image Analysis

M Boublik,J Frank,A Verschoor,M Radermacher,J F Hainfeld,T Wagenknecht,G T Oostergetel,J S Wall

doi:10.1007/978-1-4612-4884-2_4

M Boublik, J Frank + Show 6 more

https://doi.org/10.1007/978-1-4612-4884-2_4

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Publication Date: Jan 1, 1986

Citations: 8

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High-resolution electron microscopy plays a leading role in the structural analysis of biological macromolecules and is the most direct method for obtaining detailed information on the morphology, topography of the components, and functional sites of ribosomes. Electron microscopy (EM) has been important also for the interpretation of data obtained by a variety of physico-chemical techniques (for references see Chambliss et al., 1980; Liljas, 1982; Wittmann, 1983) on ribosomal protein locations, relative protein-protein distances, and protein-RNA binding sites, data which are more valuable when mapped within a well-defined structural framework provided, at present, by EM.KeywordsRibosomal SubunitElectron Energy Loss SpectroscopyDictyostelium DiscoideumBaby Hamster KidneyBaby Hamster Kidney CellThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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