Abstract
The super-relaxed (SRX) state was recently discovered in cardiac muscle fibers as an OFF state of myosin where the myosin S1 heads have reduced ATPase activity. The SRX state is thought to be a regulatory state of myosin heads that modulates the availability of functionally accessible myosin heads. A hypothesis is that the protein-protein interactions which form the SRX state are related to the interacting-head motif (IHM) state of myosin in which the S1 heads are folded back onto their coiled-coil S2 tails due to head-to-head interactions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
