Abstract
Structural studies of PML nuclear bodies in polyomavirus infected cells
Highlights
Numerous copies of rDNA genes form nucleolar organizer regions (NORs) on chromosome and give rise to the interphase nucleoli
We found that Mouse polyomavirus (MPyV) infection causes multiplication and enlargement of ProMyelocytic Leukemia Nuclear Bodies (PML NBs)
We observed the accumulation of MPyV virions around and inside of PML NBs
Summary
Numerous copies of rDNA genes form nucleolar organizer regions (NORs) on chromosome and give rise to the interphase nucleoli. Structural studies of PML nuclear bodies in polyomavirus infected cells ProMyelocytic Leukemia Nuclear Bodies (PML NBs) are distinct dynamic nuclear substructures
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