Abstract
The zinc oxide-titanium dioxide-graphene oxide-chitosan (ZTGCO) nanocomposites were synthesized via the chemical precipitation method. The synthesized nanocomposites were characterized by XRD, FTIR, DRS, FESEM, EDAX and PL. The XRD patterns of ZTGCO nanocomposites showed Wurtzite hexagonal structure. The FT-IR spectra represent the various stretching vibrational bands of ZnO, TiO2, GO and chitosan. The FESEM images revealed that the ZTGCO nanocomposites were in the cauliflower structure. The EDS spectrum showed elemental compositions of ZTGCO with oxygen vacancies. The antibacterial potential of the ZTGCO nanocomposites achieved against S. aureus and E. coli results showed the ZTGCO had more antibacterial activity than the standard antibiotic amoxicillin. The anticancer activity of the ZTGCO nanocomposites was studied in human liver cancer cells (A549) and the IC50 concentration value was observed at 48.67 μg/mL.
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