Abstract
We described three types of mitochondria, differing in shape, size and density of cristae. During subacute administration, sydnocarb has cardiotoxic effect in form of degradation of mitochondria and mitochondrial cristae. Due to sydnocarb-induced vasodilatation and swelling of cardiomyocytes, the most sensitive to hypoxia were type-1 mitochondria. It was reported not only about destruction of cristae, but also mitochondrial degradation in some areas of cardiomyocytes. The least sensitive to increasing hypoxia were type-3 mitochondria.
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