Abstract
Six new monomeric, tetrameric, and polymeric organotin(IV) derivatives of sodium 3-(benzo[d][1,3]dioxol-4-yl)propanoate (NaL) have been synthesized and characterized by various analytical techniques. These compounds show different structural behavior in solution and solid state as confirmed by NMR and X-ray single-crystal analysis. Antimicrobial and antitumor activities are mainly governed by diffusion, lipophilicity, geometry, and steric factors. The high antitumor and antifungal activities of some of these organotin compounds demand further investigations to commercialize them as new tin-based drugs.
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