Strontium phosphate/functionalized carbon nanofiber composite: A promising electrode material for amperometric detection of flufenamic acid

Abstract

Anti-inflammatory drug pollution and its potentially disastrous consequences have recently emerged as a major health issue worldwide because of its widespread use in inadequate environments. Among, Flufenamic acid (FFA) is a class of anti-inflammatory drugs widely used for therapeutic treatments, and its over usage causes severe issues in the biological systems. In this work, a particle–like strontium phosphate (Sr2P2O7) was prepared. The efficiency was increased by making a composite with functionalized carbon nanofiber (F-CNF) and used to detect FFA. The prepared individual materials (Sr2P2O7 and F-CNF) and the composite (Sr2P2O7@F-CNF) were confirmed by various spectroscopy techniques. The electrochemical studies of Sr2P2O7@F-CNF were done by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). A sensitive i-t amperometry technique was used for the determination of FFA. The attained results show that Sr2P2O7@F-CNF shows a higher active surface area (A= 0.197 cm2), a wide linear range of 0.001–80.8 µM, a low detection limit of 0.9 nM, and higher selectivity. Finally, the Sr2P2O7@F-CNF was taken to the real-time analysis with the water and urine samples. The result shows an acceptable recovery range of ± 97.50–99.66 % for the water and urine samples.