Abstract
PurposeTo investigate the correlation between strabismus and the severity of PVL based on magnetic resonance imaging (MRI) findings. Although strabismus is commonly associated with periventricular leukomalacia (PVL), its clinical features are not well established.MethodsIn this cross‐sectional study, 73 consecutive patients who visited the Department of Ophthalmology and were diagnosed with PVL were included. The severity of PVL was graded based on the MRI findings of the patients. All of the patients underwent complete ophthalmic examination, and strabismus was characterized in terms of direction, constancy, and angle of deviation. The prevalence and the characteristics of strabismus and their correlation with the grade of PVL were investigated.ResultsThe perinatal characteristics did not differ between different grades of PVL. Refractive errors, found in 56 (76.7%) patients, did not differ between the grades of PVL either. Strabismus was observed in 38 (52.1%) patients, and its prevalence increased with the grade of the disorder; 20 patients had exotropia and 18 had esotropia. Constant strabismus was found more frequently in patients with higher grade PVL. However, the direction and angle of deviation did not differ depending on the grade of PVL.ConclusionsThe prevalence of strabismus was higher among patients with PVL than among healthy individuals and increased with the severity of PVL. The severity of PVL might be related to the presence and constancy of strabismus. Early ophthalmic evaluation is necessary in children with PVL, especially in those with higher grades of the disease.
Published Version
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