Storage life and cost analysis of 0.9% sodium chloride solution in 42 ℃ couveuse

Abstract

Objective To explore the storage life and cost analysis of 0.9% sodium chloride solution in 42℃ conveuse. Methods A total of 80 bottles of 0.9% sodium chloride solution had been selected as research sampling, and the SAS 9.2 were used to randomly divide them into control group (put sampling in clean laminar flow operation room at room temperature) and experimental group (put in 42 ℃ conveuse) on average. Eight bottles of each group were took out for the number of colony examination after germiculture and the change of pH value (at the beginning of 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks experiment). Basis on the previous experiment, we selected 12 operating room and randomly divided into A group and B group on average. A conveuse provided warm 0.9% sodium chloride solution, which had three days storage life in A group, but B conveuse offered warm 0.9% sodium chloride solution of 4 weeks storage life. Results The results of germiculture were negative in both group. The 5 time point of pH values were (6.35±0.29), (6.32±0.04), (6.23±0.20), (6.29±0.35), (6.36±0.32) at the control group, while these of experimental group were (6.37±0.42), (6.31±0.11), (6.39±0.21), (6.42±0.45), (6.60±0.32)and at the same time point the pH value of two groups had no statistical significance (t=0.110 8, 0.241 7, 1.561 0, 0.645 0, 2.111 0; P>0.05). Compared with A group-consumed (2 761±118) bottles, cost (11 042±470) Yuan, B group consumed (1 466±205) bottles and cost (5 862±820) Yuan with statistical significance between two groups (t=13.41; P<0.01). Conclusions The preservation of 0.9% sodium chloride solution in 42 ℃ conveuse can be maintained 4 weeks and reduced cost by the decreasing the number of usage, and the testing norm is accord with the acquirement of pharmacopeia. Key words: 0.9% sodium chloride solution; Storage life; Germiculture; pH value; Cost