Abstract

The stoichiometric balances and absolute stability constants of some amines (atropine, chlorpheniramine and its maleate salt, dextromethorphan hydrobromide, methapyrilene hydrochloride, and quinine and its hydrochloride salt) were determined, using chloroform as the solvent. In chloroform, bromthymol blue was unable to replace the acid part of the amine salts. Nevertheless, the addition of water appears to help this replacement by separating the charges. The absolute stability constant values (between 2.5 × 104 and 6.0 × 1010) indicate that the compounds formed by reacting amines with bromthymol blue are complexes in nature rather than the salts.

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