Stochastic resonance in a time-delayed tumor cell growth system driven by additive and multiplicative noises

Abstract

In this paper, the stochastic resonance (SR) phenomenon in a time-delayed tumor cell growth system subjected to a multiplicative periodic signal, the multiplicative and additive noise is investigated. By applying the small time-delay method and two-state theory, the expressions of the mean first-passage time (MFPT) and signal-to-noise ratio (SNR) are obtained, then, the impacts of time delay, noise intensities and system parameters on the MFPT and SNR are discussed. Simulation results show that the multiplicative and additive noise always weaken the SR effect; while time delay plays a key role in motivating the SR phenomenon when noise intensities take a small value, it will restrain SR phenomenon when noise intensities take a large value; the cycle radiation amplitude always plays a positive role in stimulating the SR phenomenon, while, system parameters play different roles in motivating or suppressing SR under the different conditions of noise intensities.