Abstract
The role of stochastic dynamics in protein molecules is considered in order to explain the specific functions of ionic channels in biological membranes: conductivity, selectivity and gating. The events that govern the recognition and transfer of specific ions are very fast and should involve the small-scale dynamics. The essential features of these events may be described on the basis of the Debye model of liquid dielectrics. In contrast, the processes which control the gating (switching the channel from closed to open state) are probably associated with the large-scale fluctuations. Their mechanism is suggested to involve the non-linear interactions between the ion flux and protein conformational modes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
