Abstract

Core–corona inversion of micelles of diblock copolymer poly(acrylic acid)‐block‐poly(N‐isopropylacrylamide) (PAA‐b‐PNIPAM), has been successfully realized by switching either pH or temperature. The strong interaction of doxorubicin with the PAA block and the pH‐sensitive drug release from the polymer make the system very useful as a controlled drug delivery system. The encapsulation of hydrophobic Nile Red molecules above the lower critical solution temperature of PNIPAM suggests that this polymer may be useful for removing hydrophobic pollutants. image

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