Abstract
In a previous report from our laboratory it was shown that treatment of monolayer cultures of Chang human liver cells with deoxyadenosine at concentrations which inhibited cell proliferation induced a marked increase in the specific activity of thymidine kinase [ 11. In recent work it has been found that deoxyadenosine has a similar effect on the activity levels of dTMP kinase and dCMP deaminase, two other enzymes of the pathways for production of deoxythymidine triphosphate. The experimental results are reported in the present communication.
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