Sterilizing effects of 5% Anerdian type 3 disinfectant dilution used in conjunctival sac before cataract surgery

Abstract

Objective To compare the sterilizing effects of 5% Anerdian type 3 disinfectant dilution and 0.5% tobramycin solution used in conjunctival sac before cataract surgery. Methods Ninety cataract pa-tients ( 102 eyes) who had undergone phacoemuisification aspiration with intraocular lens insertion received 0.3% levofloxacin ophthalmic solution in the operative eye for three days before surgery and were divided into two groups randomly: the patients in one group were treated with diluted Anerdian eyewash,and those in the second group with diluted Tobramycin eyewash,immediately before the surgery. Conjunctival cultures were obtained from the operative eye before and after eyewash to observe the topical complication. Results Con-junctival cultures were positive for 10 (20%) of the Anerdian-treated eyes and 9 (17.3%) of the to-bramycin-treated eyes before eyewash. While after eyewash,the incidence of positive cultures decreased for both groups. No culture-positive was found in the Anerdian-treated group compared with 3 (5.8%) eyes in the tobramycin-treated group. There was no significant difference in culture positivity between two groups. The cultures principally showed growth of Staphylococcus epidermidis. And we disclosed no toxic or allergic reac-tion in both groups 6-month post-operatively. No significant difference were seen in BUT and Sit between two groups at day 1 postoperatively. The checking data of Sit and BUT on 7-day,30-day and 6-month postopera-tively in Anerdian eyewash patient is closed to reported. Some bacterial strains were resistance to antibiotics.Conclusion Irrigation of the conjunctival sac with a 20-fold-diluted Anerdian type 3 solution immediately pri-or to cataract surgery is recommended. Key words: Anerdian; Coniunctival sac disinfection; Bacterial culture