Abstract
The exchange of hydrogen between (S)‐chlorosuccinate and water in the presence of succinate dehydrogenase has been studied by spectrometry (mass, nuclear magnetic resonance, and optical rotatory dispersion). It is concluded that (a) the two hydrogen atoms exchanged are the methine hydrogen and HR of the methylene group; (b) processes exchanging one and two atoms proceed simultaneously; (c) the methine hydrogen is exchanged faster than HR; (d) all molecules in which HR has been exchanged have also exchanged the methine hydrogen.
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