Abstract
<p>The chemical structure and absolute configuration of a<br />novel benzoic acid (1) which is the secondary metabolites from the<br />marine fungus Penicillium chrysogenum SYP-F-2720, has been determined<br />by experimental spectroscopic data and quantum chemical<br />calculations of its electronic circular dichroism (ECD). The configurational<br />assignments were further confirmed by the highly consistent<br />spectra between natural compound and synthetic compound which<br />from raw material with a definite configuration. Furthermore, The<br />target compound exhibited more significant anti-inflammatory and<br />analgesic activities than aspirin when administered at 100 mg/kg,<br />however, it behaved no ulcerogenic effect.</p>
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