Abstract

BackgroundStentless aortic valve replacement (SAVR) became a common surgical procedure to treat aortic valve disease, as it offers larger orifice area and improved hemodynamics. The aim of our single-centre retrospective study was to assess long term results of first generation stentless aortic valves in young patients, where mechanical prostheses are considered first line therapy.MethodsFrom 1993 to 2001, 188 (149 male and 39 female) patients (≤60 years) underwent SAVR. Indications were in 63.3% stenosis or mixed lesions and in 36.7% isolated regurgitation. Mean age of patients at surgery was 53.1 ± 7.1 years. Associated procedures were performed in 60 patients (31.9%). Follow-up data were acquired through telephone interviews. Follow-up was 90.4% complete at a mean of 8.8 ± 4.7 years. Total follow-up was 1657.6 patient-years with a maximum of 17 years.ResultsOverall hospital mortality was 3.2% (2.5% for isolated SAVR). Overall actuarial survival-rate at 10/15 years and freedom from reoperation at 10/14 years were 73.0% ± 3.5%/ 55.8% ± 5.4% and 81.0% ± 3.4%/ 58.0% ± 7.5%, respectively. For isolated SAVR, actuarial survival at 10/15 years and freedom from reoperation at 10/14 years were 70.1% ± 4.4%/ 64.1% ± 4.8% and 83.1% ± 4.0%/ 52.9% ± 9.0%, respectively. Reoperation was performed in 42 patients (22.3%) due to structural valve deterioration and endocarditis. Age (≤50 years) and associated procedures did not significantly lower survival and freedom from reoperation, however, small prosthesis sizes (≤25 mm) did.ConclusionIn patients aged 60 and younger, SAVR provides reliable long-term results especially for larger aortic valves.

Highlights

  • Stentless aortic valve replacement (SAVR) became a common surgical procedure to treat aortic valve disease, as it offers larger orifice area and improved hemodynamics

  • Implantation of bioprosthetic aortic valves is still controversial in younger patients

  • Either the patient’s explicit desire for bioprosthetic AVR or a contraindication to oral anticoagulation caused a decision for SAVR

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Summary

Introduction

Stentless aortic valve replacement (SAVR) became a common surgical procedure to treat aortic valve disease, as it offers larger orifice area and improved hemodynamics. The aim of our single-centre retrospective study was to assess long term results of first generation stentless aortic valves in young patients, where mechanical prostheses are considered first line therapy. Stentless aortic valve replacement has become a common surgical treatment of aortic valve disease. These prostheses are designed to allow physiological flow patterns by avoiding an obstructive stent [1]. Various studies revealed controversial results comparing stented and stentless prostheses. In a prospective randomized trial, SAVR showed a midterm survival advantage compared to stented aortic valve replacement (AVR) [3]. Implantation of bioprosthetic aortic valves is still controversial in younger patients. The American Heart Association and the American College of Cardiology recommend bioprosthetic aortic valves in patients above

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