Abstract
Polycystic ovarian syndrome is a complex, polyfactorial condition which involves multiple genes and body systems. The development of PCOS may be attributed to several factors such as genetics, epigenetics, hyperandrogenism, insulin resistance, and environmental factors. Current medication used to treat PCOS have been shown to be ineffective and thus the development of novel therapeutics is necessary. Numerous types of stem cells can play a therapeutic role in the treatment of PCOS including mesenchymal stem cells, bone marrow stromal cells, adipose derived stem cells, menstrual blood derived mesenchymal stem cells, umbilical cord mesenchymal stem cells, amniotic fluid stem cells. Potential limitations include transplant rejection, transportation and storage difficulties, commercialization difficulty, and safety issues without monitoring.
Published Version
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