Abstract

It is little known about the food intake status in patients with Crohn’s disease (CD). The aim of this study was to clarify the food intake status in patients with CD. The subjects were thirty patients with CD who have been followed up at our department. Food intake status per week and implementation status of elemental nutrition (EN) were investigated. 12 patients (40.0%) were received EN more than 900 kcal (High EN group), 5 patients (16.7%) were received EN less than 900 kcal (Low EN group) and 13 patients (43.4%) did not perform EN (Non-EN group). The High EN group were more likely to take calories per day than Low EN group (P<0.0001) and Non-EN group (P<0.0001). The intake of protein and carbohydrate were significantly higher in the High EN group than in the Non-EN group (P<0.0001). In contrast, the intake of fat and food fiber per day was significantly lower in the High EN group than in the Non-EN group (P=0.0006, P=0.007). The enforcement of EN in patients with CD is effective for maintaining good nutritional statement. As for the patients with CD, EN should be performed for sustaining clinical remission and good nutritional status.

Highlights

  • Crohn’s disease (CD) is a chronic inflammatory digestive disease

  • Because nutrition therapy is a safe, effective therapy, it is used for the induction and maintenance therapy especially pediatric patients with CD [8,9]

  • Many patients receive nutrition therapy in Japan, it is little known about the food intake status in patients with CD

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Summary

Introduction

The natural course of CD is usually progressive, disable, relapsing and most patients with CD receive intestinal surgery in their life [1,2]. Powerful therapy such as immunomodulators and anti TNFalfa antibody have possibility to change the natural course of CD. A large cohort suggest that the surgery to CD recently has been reduced by effective medical treatments [3]. Because nutrition therapy is a safe, effective therapy, it is used for the induction and maintenance therapy especially pediatric patients with CD [8,9]. Many patients receive nutrition therapy in Japan, it is little known about the food intake status in patients with CD

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