Statistical Association Between Age Groups, Body Mass Index and Cancer Grade with Serological Concentrations of Immunological Biomarkers (Interleukin IL-1β, IL-6) among Females with Breast Cancer

Abstract

Statistical association between age groups, body mass index and cancer grade with serological concentrations of immunological biomarkers (interleukin IL-1B, IL-6) among females with breast cancer was carried out in this study. The total number of breast cancer patients involved in this study are 80 individuals were taken from Basrah oncology center in Basrah province, the age of patients ranging from 20–80 years and 80 individuals considered as control group after they were checked and confirmed to be free from any chest or any other health problems. the lowest rate of breast cancer females was found within the age groups 20–29 years (2.5%), and highest rate in age group 50 to 59 years (32.5%). The levels of Interleukin 1 beta (IL-1β) pg/mL were (5.04 pg/mL) in (>60) years and 2.87 pg/mL in age 20–29 yrs., with significant differences. The levels of IL-1β fluctuated between stages with high value in stage IV was (2.675 pg/mL). The levels of interleukin IL-6 were high value in (>60) years (6.65 pg/mL) with p = 0.01. The levels of IL-6 show high value in stage IIIC (18.5650 pg/mL). The mean of IL-6 pg/mL with body mass index, shown overweight recorded (6.797 pg/mL).