Abstract
Summary 40 autopsied cases of demyelinating diseases in Japan were classified, based on autopsy findings, into three groups; 18 cases of multiple sclerosis (MS) group, 13 cases of neuromyelitis optica (NMO) group and 9 cases of intermediate form. The clinical features were compared in the MS and NMO groups by Chi square test. By “component analysis”, it was shown that the MS and NMO groups could be discriminated clinically with high reliability. In the component analysis, disturbance of consciousness, emotional disturbance, bulbar signs and incoordination were the significant items for the MS group, and onset with fever or infection, bilateral simultaneous visual impairment and infection in the past history for the NMO group. (5) The component analysis was proved to be applicable in the clinical differentiation of MS and NMO.
Published Version
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