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EFSA JournalVolume 8, Issue 12 1955 StatementOpen Access Statement on the assessment of the safety of Cylactin® (Enterococcus faecium) used in animal nutrition EFSA Panel on Additives and Products or Substances Used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances Used in Animal Feed (FEEDAP)Search for more papers by this author EFSA Panel on Additives and Products or Substances Used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances Used in Animal Feed (FEEDAP)Search for more papers by this author First published: 21 December 2010 https://doi.org/10.2903/j.efsa.2010.1955Citations: 5 Panel members: Gabriele Aquilina, Georges Bories, Paul Brantom, Andrew Chesson, Pier Sandro Cocconcelli, Joop de Knecht, Noël Albert Dierick, Mikolaj Antoni Gralak, Jürgen Gropp, Ingrid Halle, Reinhard Kroker, Lubomir Leng, Anne-Katrine Lundebye Haldorsen, Alberto Mantovani, Miklós Mézes, Derek Renshaw and Maria Saarela Correspondence: feedap@efsa.europa.eu Acknowledgement: The Panel wishes to thank the members of the Working Group on Microorganisms, including Roland Leclercq, Atte von Wright and Guido Rychen, for the preparatory work on this scientific opinion for the support provided to this scientific opinion. Adoption date: 7 December 2010 Published date: 21 December 2010 Question number: EFSA-Q-2010-01264 On request from: European Commission AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References Bismuth R and P. Courvalin, 2009. Aminoglycosides and Gram-positive bacteria. In: Antibiogram. Eds P. Courvalin, R. Leclercq, L. Rice. 2009, ASM Press, pp. 213– 224. Costa, Y., Galimand, M., Leclercq, R., Duval, J., and Courvalin, P. 1993. Characterization of the chromosomal aac(6′)-Ii gene specific for Enterococcus faecium. Antimicrobial Agents and Chemotherapy, 37, 1896– 1903. DANMAP (Danish Integrated Antimicrobial resistance Monitoring and Research Programme), 2009, online. Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, foods and humans in Denmark. Available from www.danmap.org. EC (European Commission), 2001, updated 2003, online. Opinion of the Scientific Committee on Animal Nutrition on the criteria for assessing the safety of micro-organisms resistant to antibiotics of human clinical and veterinary importance. Available from europa.eu.int/comm/food/fs/sc/scan/out108_en.pdf. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), 2005. Scientific Opinion on the updating of the criteria used in the assessment of bacteria for resistance to antibiotics of human and veterinary importance. The EFSA Journal, 223. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), 2008a. Technical guidance - Update of the criteria used in the assessment of bacterial resistance to antibiotics of human or veterinary importance. The EFSA Journal, 732, 1– 15. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), 2008b. Guidance for the preparation of dossiers for zootechnical additives. The EFSA Journal, 776, 1– 17. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), 2010. Scientific Opinion on the safety and efficacy of Cylactin® (Enterococcus faecium) for chickens for fattening. EFSA Journal, 8(7): 1661. [13 pp.]. Galimand M., Schmitt E., Panvert M., Douthwaite S., Mechulam Y. and Courvalin P., 2010, in press. Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM. RNA. Moellering R.C. Jr., Korzeniowski O.M., Sande M.A. and Wennersten C.B., 1979. Species-specific resistance to antimicrobial synergism in Streptococcus faecium and Streptococcus faecalis. Journal of Infectious Diseases, 140, 203– 208. Citing Literature Volume8, Issue12December 20101955 ReferencesRelatedInformation

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