Abstract
Malignant neoplasms of the lip are a rare type of tumor. State reporting provides only a set of data for calculating incidence rates. The Population-Based Cancer Registry (PCR) database developed by us at the level of the Northwestern Federal District of the Russian Federation allowed, for the first time in Russia, to calculate a set of analytical indicators, such as the median survival, one-year and five-year cumulative survival rates of lip cancer patients, taking into account the detailed localization and histological structure.
 The aim of the study was to investigate the level and trends in survival of lip cancer patients in the Northwestern Federal District of the Russian Federation considering the localization and histological structures and the stage of the disease.
 The material of the study was the Population-based Cancer Registry of the Northwestern Federal District of the Russian Federation. Data processing was carried out using the methodology recommended by the International Association of Cancer Registries under the EUROCARE program.
 Unfavorable trends in the lip cancer incidence rate have been established in Russia and the Northwestern Federal District of the Russian Federation. The median survival remained within 68 years. Survival rates of patients have indicated a high level of treatment of patients with malignant lip neoplasms at the level of the Northwestern Federal District. Survival of patients in the first year of observation was: observed 89.3%, relative 93.8%. The five-year observed survival did not reach 50%, the relative exceeded 60%.
 Detailed localization development of the PCR data has revealed that patients with malignant neoplasms of the outer surface of the lower lip (C00.1) account for 60%. Histological characteristics of the registered patients have been significantly improved.
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