Stages of the evolution of thymus atrophy in children in different cities of Kyrgyzstan

Abstract

Introduction and Aim: Thymus atrophy occurs in response to the stress of any etiology such as cold, burn, infection, trauma, pain, and psychogenic stress. The objective of the study is to evaluate the thymus gland in children aged 7–12 years from Kyrgyzstan.
 
 Materials and Methods: The present study assessed the anatomy of the thymus gland on 35 cadavers of children aged 7–12 years from 2015 to 2020. Anatomical methods including preparation, weighing, and measurement, and histological methods including hematoxylin-eosin staining were performed.
 
 Results: In children aged 7–12 years, it was found that in the thickness of the cerebral layer, there is the growth of thymic corpuscles, blood capillaries, and lymphatic slits. The level of cells in the cerebral layer is diverse, there are lymphocytes in large numbers, larger light epithelial and reticular cells, as well as macrophages. In the cortical zone, the cellular composition is mainly lymphoid cells, and mitosis was found in some of them.
 
 Conclusion: In this study, comparatively, the cortical zone prevails over the cerebral one. At this age, the thymus begins to atrophy, as well as the growth of adipose tissue.