Abstract
As a drug product for vitreous replacement, the stability of polydimethylsiloxane (PDMS) during storage is very necessary. PDMS must be stable both chemically and physically during the storage process according to WHO standards. This is necessary to maintain security and regulate the drug supply. Our research shows that low-and medium-viscosity PDMS produced from low-grade octamethylcyclotetrasiloxane (D4) monomer have good stability and storage for 15 months. The optimal time for stability and storage of this PDMS is 5 months. Changes in viscosity values occur due to a very slow chain growth from 5 until 15 months. However, a longer assessment time and other tests are needed to complete the material stability information.
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