Abstract
A new stability indicating method was developed for the estimation of trifluoperazine HCl in API, this method was also successfully utilized for the estimation of drug in tablet dosage forms. All the methods were utilized for the degradation of drug i.e. 0.1 N HCl, 0.1 N NaOH, 3 % H2O2, thermal and photodegradation. Drug peak was found to be seperated from all the degradants with resolution of more then two. This method was also used for the estimation of Trifluoperazine HCl in tablet dosage forms. The method was found to be simple, precise, specific and accurate. Developed HPLC method is able to separate all degradants produce form any stress condition from drug peak by resolution of more than 2. The order of stability trifluoperazine HCl was found to be H2O2andgt;alkali acid heat. The newly developed method can be used for routine analysis for the estimation of Trifluoperazine HCl in bulk and tablet dosage form in pharmaceutical industry.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
