Abstract
SEVERAL authors1,2 have reported that the antibiotic tetracycline enhances the removal of radiostrontium from mice. Theoretical work3,4 has indicated that a suitable reagent for the removal of radiostrontium from the mammalian skeleton should have a greater affinity for strontium than for calcium. We have, therefore, examined the chelation with tetracycline of calcium and strontium and also, for comparison, magnesium. The only reported stability constants for tetracycline chelates are those determined by Albert5 for the chelates of aluminium and some transition metals. The acid dissociation constants for the hydrochloride derivative have, however, been determined by Albert5 and by Stephens et al.6.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.