Abstract
Negative energy balance (NEB) is a physiological state that arises during the transition from pregnancy to lactation in dairy cows. This transition period is associated with a decline in dry matter intake and an increased demand for energy sources for milk production. Ketosis, a metabolic disorder, often emerges shortly after calving and is characterized by reduced glucose levels, depleted liver glycogen, and elevated ketone body concentrations. The study aimed to investigate the impacts of ketosis on milk yield, reproductive parameters, and postpartum metabolic diseases in cows with subclinical and clinical ketosis. The study involved 267 healthy pregnant Holstein dairy cows in the second and third lactation periods. Groups were formed based on postpartum third-day beta-hydroxybutyrate (BHBA) levels. The groups included control (BHBA < 1.2 mmol/dL), subclinical ketosis (BHBA = 1.2-2.4 mmol/dL), and clinical ketosis (BHBA > 2.4 mmol/dL) groups. Results indicated that higher body condition scores (BCS) during calving were associated with an increased risk of postpartum ketosis (p
Published Version
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