Abstract
Introduction. Malignant transformation in a mature cystic teratoma of the ovary is a rare complication. Squamous cell carcinoma is the most common transformation. We describe a new case of squamous cell carcinoma arising in a mature cystic teratoma. Case Report. A premenopausal 52-year-old female patient is diagnosed with vaginal bleeding. According to examination made on the women and the pelvic scanning, 7 cm mass is found on the right adnexa of the patient. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic lymph node dissection, and debulking were the treatments completed on the patient. According to histopathological diagnosis, squamous cell carcinoma arising in a mature cystic teratoma is diagnosed as a reason for the mass in the right adnexa of the patient. Conclusion. The prognosis of the malign transformation of MCT depends on surgery stage; however it is extremely poor. The patient should receive chemotherapy regardless of stage. We have decided to administer second cycle carboplatin and paclitaxel treatments on the patient.
Highlights
Malignant transformation in a mature cystic teratoma of the ovary is a rare complication
The most common malignant transformation is squamous cell carcinoma (SCC) which is around 70–80% of malign transformation cases
We presented a case about this rare tumor, squamous cell carcinoma arising in a mature cystic teratoma with analyzing related literature
Summary
Mature cystic teratoma (MCT) is the most common germ cell tumor of the ovary. The clinical presentation, symptoms, and complications show similarities to some other ovarian tumors Such common symptoms are abdominal pain (54%), mass (31%), constipation, bleeding, weight loss, urinary frequency, and fever. We presented a case about this rare tumor, squamous cell carcinoma arising in a mature cystic teratoma with analyzing related literature. A perimenopausal 52-year-old woman, gravida 3, para, was admitted by our clinic in April 2012 with a onemonth history of vaginal bleeding and progressive abdominal discomfort She dose not have known medical history, medication, drinking alcohol problem, and family history of cancer. Intraoperative pathology consultation revealed a malignant epithelial tumor consistent with squamous cell carcinoma arising in a mature cystic teratoma. A final diagnosis of malignant transformation of moderately differentiated squamous cell carcinoma in a mature cystic teratoma with extensive necrosis was made (Figures 1 and 2). Later the patient received second cycle treatment without any problem
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