Sporadic gastric polyps: endoscopic and histological features, prognosis. A report concerning 75 cases

Abstract

In a retrospective study of sporadic gastric polyps carried out between 1997 and 2007, we analysed the demographic, endoscopic and histological features of 75 patients with polyps. This study revealed 56 hyperplastic polyps (HP), 17 adenomatous lesions (AP) and 2 inflammatory fibroid polyps (IFP). In hyperplastic polyp, the average age was 71 years ± 15 with a sex ratio 1: 1. The gastric antrum was the main site affected by HP, which measured an average 10 mm. In the 56 cases of HP, removal was by endoscopy in 41% and surgery in 5.3% of cases. The average age for patients presenting with AP was 77 years ± 13 years, with a sex ratio 3: 1. The gastric antrum was the main site of involvement and 90% measured more than 10mm. The adenoma was removed by endoscopy in 57% of the cases and by surgery in 21%. The IFP concerned two patients. The polyps were located in the antrum and measured ≥10 mm. They were removed by surgical treatment. Advanced dysplasia was diagnosed in 3.6% of HP and 18% of AP and carcinoma in 12% of AP. None of the IFP presented signs of dysphasia. Intestinal metaplasia was found in 14% of the HP and 19% of the AP, whereas gastric atrophy was found in 19% and 89% of cases respectively. The adenomas were intestinal in 88% of patients and pyloric in 12%. Dysplasia lesions occurred mainly in intestinal AP.