Abstract
Background/aims: Gastric polyps are usually asymptomatic and found in approximately 2-6% of upper gastrointestinal endoscopic procedures. Hyperplastic polyps and fundic gland polyps are the two most common subtypes of gastric polypoid lesions. The aim of this study was to determine the characteristics of patients with gastric polyps diagnosed through endoscopy, the histological characteristics and location of the polyps and the presence or not of Helicobacter pylori infection. Materials and Methods: Dyspeptic patients with gastric polypoid lesions detected by upper gastrointestinal endoscopy at Dokuz Eylul University Gastroenterology Clinic between January 2010 and June 2012 were analyzed retrospectively. Data including the patients' age and sex, the number, location and histopathologic type of polyps and the presence of Helicobacter pylori infection were recorded. Eighty patients with gastric polypoid lesion (63 F, 17 M, mean age: 60.1±12.8 years) were enrolled in the study. One-hundred and seventy-four gastric polypoid lesions were identified in 80 patients. Results: Polypoid lesions were commonly located in the corpus (64%), followed by fundus (24%) and antrum (20%). The most frequently encountered histopathologic subtype of gastric polypoid lesions was hyperplastic polyp (48%), followed by foveolar hyperplasia (21%), fundic gland polyps (20%), neuroendocrine tumor (9%), adenoma (1%), hamartomatous (1%) and inflammatory fibroid polyp (1%). Hyperplastic polyps were primarily single, whereas fundic gland polyps tended to be multiple. Hyperplastic polyps were associated with Helicobacter pylori infection, chronic active gastritis and intestinal metaplasia. Conclusions: The most frequently encountered histopathologic subtype of gastric polypoid lesions was hyperplastic polyp. The prevalence of neuroendocrine tumors seems to be higher than that reported earlier, most likely because of the widespread use of proton pump inhibitors.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
