Spontaneous reporting of adverse drug reactions: nurses’ perception

Ouassima Erefai,Sanou Khô Coulibaly,Abdelmajid Soulaymani,Abdelrhani Mokhtari,Hinde Hami,S Bourekkadi,A Mokhtari,K Slimani,A Soulaymani,H Hami

doi:10.1051/e3sconf/202131902005

Abstract

Introduction: Spontaneous reporting of adverse drug reactions is the basis of pharmacovigilance, the main objective of which is to ensure the safe use of drugs, particularly cytotoxics, through continuous monitoring of adverse events caused by them. The aims of this study were to investigate the perception of nurses towards pharmacovigilance, and identify reasons for under-reporting of adverse reactions to cytotoxic drugs in Morocco. Methods: Individual semi-structured interviews were conducted with 10 nurses in charge of administering cytotoxics drugs in the Pediatric Hemato-Oncology Department of the Children’s Hospital in Rabat in 2019. The interviews were recorded, then transcribed and analyzed. Results: From this study, positive attitudes towards the reporting of adverse drug reactions by nurses were shown. Nevertheless, an insufficient level of knowledge of pharmacovigilance by the participants was showed. Lack of training was the main cause of this lack of knowledge. Conclusion: This study showed a positive perception of nurses towards pharmacovigilance and ADR reporting despite insufficient knowledge. The integration of pharmacovigilance modules in the training curriculum of nurses will help to improve ADR reporting.

Highlights

Spontaneous reporting of adverse drug reactions is the basis of pharmacovigilance, the main objective of which is to ensure the safe use of drugs, cytotoxics, through continuous monitoring of adverse events caused by them
Pharmacovigilance is based on spontaneous reporting of adverse drug reactions (ADRs) by health professionals and patients, many studies have shown that ADRs are largely under-reported [8,9,10,11]
This is a qualitative study through semi-structured interviews, conducted face-to-face with nurses responsible for the administration of cytotoxics and who have worked at least one year in the Pediatric HematoOncology Department in Children’s Hospital in Rabat, Morocco, in 2019

Summary

Introduction

Spontaneous reporting of adverse drug reactions is the basis of pharmacovigilance, the main objective of which is to ensure the safe use of drugs, cytotoxics, through continuous monitoring of adverse events caused by them. The aims of this study were to investigate the perception of nurses towards pharmacovigilance, and identify reasons for under-reporting of adverse reactions to cytotoxic drugs in Morocco. Results: From this study, positive attitudes towards the reporting of adverse drug reactions by nurses were shown. Conclusion: This study showed a positive perception of nurses towards pharmacovigilance and ADR reporting despite insufficient knowledge. Pharmacovigilance is based on spontaneous reporting of adverse drug reactions (ADRs) by health professionals and patients, many studies have shown that ADRs are largely under-reported [8,9,10,11]

Objectives

Methods

Results

Conclusion