Abstract
This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. Diagnostic curetting and biopsy were performed and she was diagnosed with clear cell carcinoma of endometrium. Anti-tumour therapy was not possible because of her poor psychiatric status. 13 months later the woman died of a natural cause and at autopsy the endometrial tumour could no longer be identified. Myocardial infarction, aggravated by poor functional status of organism due to sepsis, was concluded to be the cause of death.
Highlights
Spontaneous regression of a malignant tumour is a rare and incompletely understood phenomenon
This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium
The precise mechanism of tumour regression is unknown, our case demonstrates that clear cell carcinoma of the endometrium may spontaneously regress
Summary
Spontaneous regression of a malignant tumour is a rare and incompletely understood phenomenon. It is defined as complete or partial disappearance of tumour without medical treatment, considered to be adequate for tumour disappearance. The knowledge around this topic is mainly based upon individual case reports. Due to this event happening extremely rare (the incidence of spontaneous regression has been estimated to be not more than 1 in 60,000 - 100,000 patients) [1], there are no proven data about the mechanism or inducing factors. In some cases tumour regression was preceded by surgical procedures [6][8]; the role of infectious agents and febrile reaction [9]-[13] as well as changes in metabolic processes (especially glucose metabolism) [14] [15] in the regression of cancer is well documented
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call