Split Face Comparative Study of Plasma Gel versus Non Cross Linked Hyaluronic Acid for Treatment of Static Forehead Wrinkles

Abstract

Abstract Background The entire human body is subject to changes associated with aging. Those occurring in the skin are visible, facial aging can be particularly negative since it represents the main image. Among the factors playing an important role in facial aging are exposure to ultraviolet (UV) light, smoking habits and alcohol consumption, which, together with genetic factors, can alter the rate of skin aging. Objectives The presented study aimed to compare the efficacy of the plasma filler and the non-cross linked hyaluronic acid in treating static forehead wrinkles. Patients and Methods The present study is a prospective study which included 20 adult male and female with different grades of static forhead wrinkles. Our participants range between 40 to 55 years old. This study was done in a period of 6 months starting from February 2019 to September 2019. All participant signed informed consent after explaining to them the objective of the study. An official research approval was granted from research ethical committee, faculty of medicine in Ain Shams University and fulfilled all the ethical aspects required in human research. Results So the plasma gel is as safe and efficient as non cross linked hyaluronic acid in treating static forehead wrinkles as there is no significant difference between the right and left forehead after treatment. Conclusion Plasma gel is as safe and effective as non cross-linked HA, plasma gel is cheap, available, easy promising tool to treat wrinkles.